Sarah James is an art historian and writer based in Frankfurt am Main, Germany. Received Jun 6; Accepted Dec Jordan Seiler, Underground, Giclee print with digital augmentation, ,6x,4cm 27x40in , The technological apparatus takes centre stage.
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University of Liverpool; Note the decreasing number and staining intensity of the cell nuclei as the concentration of ATRA is increased. The expression of differentiation and stem cell markers allows direct quantification of the differentiation process and can be assessed by qPCR. Chick embryos up to two thirds gestation did not require ethical approval since the change in UK legislation effective from January during the period these experiments were completed. Like Klein, Blumenfeld could dissect the mechanisms of the culture industry via the agitational strategies of the avant-garde from the inside out. The Chorioallantoic membrane of the Chick embryo to assess tumor formation and metastasis. National Center for Biotechnology Information , U.
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Received Jun 6; Accepted Dec The funding body had no role in the design of the study or collection, analysis, and interpretation of data or in writing the manuscript. It will be interesting to discover whether ATRA or other differentiation agents can reverse the effect of hypoxia and reduce or inhibit the metastasis of Neuroblastoma cells.
This article has been cited by other articles in PMC. One characteristic feature of neuroblastoma is its unusually high rate of spontaneous regression and this may be connected to the susceptibility of tumour cells to differentiate. Disobedient Curiosity. Results Assessment of ATRA effects by measuring cell proliferation and expression of differentiation markers The effect of ATRA on MNA neuroblastoma cells has been well characterised in terms of morphology and immunofluorescence of differentiation markers [ 18 — 20 ]. See lds singles online dating free